First complete genome characterization of swinepox virus directly from a clinical sample indicates divergence of a Eurasian-lineage virus

In this study, we report the complete genome sequence of swinepox virus from a clinical sample naturally occurring infection in India. The sequencing was done on Nanopore MinION sequencer Oxford Technologies. Two new annotations were added to genome. Three genes found have frameshifts, which might be importance relation infection. When compared only other reported whole virus, obtained an isolate America 1999, our is 98.19% identical at nucleotide level. average amino acid identity viral proteins, based common 149 annotations, also 98.19%, demonstrating that these viruses are distinctly divergent. Owing fact infects swine, it could not entered until introduction swine 16th century Europe. both continents continued evolve independently. divergence identified here indicates Eurasian-lineage geographically distinct American-lineage virus.